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While on a flight home from Colombia, the plane that Dr. Carrie Ross and her daughter are on is attacked by bullet ants whose sting is the most painful and deadliest on the planet. Joining forces with air marshal Ethan Hart, Dr. Ross, an entomologist, tries desperately to save the flight from disaster. In the end, their struggle brings them closer together and offers the couple hope for the future.

Gilsig brings a frantic, grounded energy to the cockpit as she battles a swarm of lethal bullet ants mid-flight. This low-budget creature feature trades logic for pure, claustrophobic terror inside a pressurized cabin.