About

Pinky and Brain are genetically enhanced laboratory mice who reside in a cage in the Acme Labs research facility. Brain is self-centered and scheming; Pinky is good-natured but feebleminded. In each episode, Brain devises a new plan to take over the world, which ultimately ends in failure, usually due to Pinky's idiocy, the impossibility of Brain's plan, Brain's own arrogance, or just circumstances beyond their control.

Instead of typical slapstick, this animated comedy relies on rapid-fire wit and elaborate, failed schemes for global domination. The comedic friction between a megalomaniac genius and his lovable, dimwitted sidekick creates a rhythmic brilliance rarely seen in children's programming.