Prescription: Murder
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In Columbo's first outing, a psychiatrist uses a patient he is having an affair with to help him kill his wife, but his perfect alibi may come apart at the hands of a seemingly befuddled LAPD lieutenant.
Director
Richard Irving
Cast
Peter Falk, Gene Barry, Katherine Justice, William Windom, Nina Foch, Virginia Gregg, Andrea King, Susanne Benton, Ena Hartman, Sherry Boucher
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In Columbo's first outing, a psychiatrist uses a patient he is having an affair with to help him kill his wife, but his perfect alibi may come apart at the hands of a seemingly befuddled LAPD lieutenant.
Director
Richard Irving
Cast
Peter Falk, Gene Barry, Katherine Justice, William Windom, Nina Foch, Virginia Gregg, Andrea King, Susanne Benton, Ena Hartman, Sherry Boucher
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Prescription: Murder is streaming on Peacock. Availability last verified February 25, 2026.
