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You can stream Eyeshield 21 (2005) on Crunchyroll with a subscription.

In Tokyo, a weak, unassertive boy named Sena Kobayakawa enters the high school of his choice, Deimon Private Senior High School. Sena's only remarkable physical abilities are his running speed and agility, which are noted by the school's American football team captain Yoichi Hiruma. Hiruma forces Sena to join the Deimon Devil Bats football team as its running back. To protect his identity from other teams who want to recruit him, Sena is forced to publicly assume the role of the team secretary and enter the field under the pseudonym of "Eyeshield 21" wearing a helmet with an eyeshield to hide his features.

A timid boy with lightning-fast reflexes finds himself coerced into a brutal American football squad by a terrifyingly brilliant captain. This high-energy underdog story trades slow-motion drama for explosive, physics-defying sprints and relentless team spirit.